Article
The Potential Role of Female Sex Hormones in Patients With Inflammatory Bowel Disease: A 2-Sample Mendelian Randomization Study.
Clinical and translational gastroenterology - 1 Aug 2024
Pan Jiaqi, Jiang Wenxi, Xin Linying, Wu Jiali, Zhu Shefeng, Liu Zhaoxue, Shen Zhe
Abstract excerpt
INTRODUCTION: An association between female sex hormones and inflammatory bowel disease (IBD) has been reported in epidemiological studies. However, a solid causal relationship has not been established. Therefore, we performed a 2-sample Mendelian randomization (MR) study to explore the causal association between genetically predicted female sex hormone exposure, especially estrogen, and IBD. METHODS: Genetic...
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