Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mendelian randomization analysis reveals causal associations between autoimmune diseases and female infertility risk.

Reproductive toxicology (Elmsford, N.Y.) - 1 Oct 2025

Wang Jinyuan, Long Haojun, Su Mingxuan, Cao Yichang, Zhou Runtang, Li Xiang, Li Jiangming, Tang Yuxia, Tang Jiayi, Wang Simin, Tang Linyue, Chen Ruxin, Deng Danqi, Tang Li

Abstract excerpt

BACKGROUND: Infertility is viewed as a significant social challenge globally. Numerous observational studies have documented the link between autoimmune diseases (ADs) and female infertility, yet the underlying cause remained unclear. The primary objective of this study was to ascertain the causal connection between ADs and female infertility. METHOD: We evaluated summary statistics from genome-wide association...

Topics

Join the communities discussing this publication.

Autoimmune Diseases
Genetic Predisposition to Disease
Genome-Wide Association Study
Infertility, Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 40615097
DOI: 10.1016/j.reprotox.2025.108984

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mendelian randomization analysis reveals causal associations between autoimmune diseases and female infertility risk.PMID 40615097Read ↗

Investigation of the Causal Relationship Between Autoimmune Diseases and Premature Ovarian Insufficiency.Semantic proximity Read ↗

Rheumatoid Arthritis and Infertility:A Mendelian Randomisation StudySemantic proximity Read ↗

The Causal Relationship Between Immune Cells and Infertility: A Mendelian Randomisation Study.Semantic proximity Read ↗

Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.Semantic proximity Read ↗

Blood-based inflammatory markers in female infertility: evidence from Mendelian randomization analysis.Semantic proximity Read ↗

Causal relationship between genetically predicted antibody-Mediated Immune Responses and female infertility.Semantic proximity Read ↗

The causal relationship of female infertility and psychiatric disorders in the European population: a bidirectional two-sample Mendelian randomization study.Semantic proximity Read ↗

The Association between Rheumatic Diseases and the Risk of Polycystic Ovary Syndrome: A Two-Sample Mendelian Randomization Analysis.Semantic proximity Read ↗

Causal Association Between Female Infertility and Circulating Immune Cells: A Bidirectional Mendelian Randomization Study.Semantic proximity Read ↗

Causal relationship between inflammatory bowel disease and sex: a Mendelian randomization study.Semantic proximity Read ↗

Juvenile idiopathic arthritis and primary ovarian failure: a two-sample Mendelian randomization analysis in a mixed-gender cohort.Semantic proximity Read ↗

Causal association between telomere length and female reproductive endocrine diseases: a univariable and multivariable Mendelian randomization analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.