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Article

Testosterone, sex hormone-binding globulin, insulin-like growth factor-1 and endometrial cancer risk: observational and Mendelian randomization analyses.

British journal of cancer - 1 Oct 2021

Mullee Amy, Dimou Niki, Allen Naomi, O'Mara Tracy, Gunter Marc J, Murphy Neil

Abstract excerpt

BACKGROUND: Dysregulation of endocrine pathways related to steroid and growth hormones may modify endometrial cancer risk; however, prospective data on testosterone, sex hormone-binding globulin (SHBG) and insulin-like growth factor (IGF)-1 are limited. To elucidate the role of these hormones in endometrial cancer risk we conducted complementary observational and Mendelian randomization (MR) analyses. METHODS:...

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Identifiers

PMID: 34363033
DOI: 10.1038/s41416-021-01518-3
PMCID: PMC8548546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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