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Article

Exploring the associations of plasma proteins with frailty based on Mendelian randomization.

BMC immunology - 23 Dec 2024

Chen Shuhui, Lin Hao, Liu Bin, Pan Hejing, Xu Yaling, Mao Yingying, Huang Lin

Abstract excerpt

BACKGROUND: Frailty is an emerging global burden of disease, characterized as an age-related clinical syndrome. Recent studies have suggested a potential link of circulating protein levels with the onset of frailty. This study aims to analyze the potential causal relationships of plasma proteins with frailty using a Mendelian Randomization (MR) study design. METHODS: Associations of plasma proteins with frailty...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39716054
DOI: 10.1186/s12865-024-00677-1
PMCID: PMC11664895

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