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Article

Protein Nutritional Status and Frailty: A Mendelian Randomization Study.

The Journal of nutrition - 11 Jan 2022

Tomata Yasutake, Wang Yunzhang, Hägg Sara, Jylhävä Juulia

Abstract excerpt

BACKGROUND: Observational studies have suggested that better protein nutritional status may contribute to prevention of frailty. OBJECTIVE: We sought to examine this hypothesis using a Mendelian randomization (MR) analysis. METHODS: We conducted a two-sample MR study using GWAS summary statistics data of the UK Biobank. We applied genetically predicted serum albumin as a primary exposure measure and serum total...

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Frailty
Genome-Wide Association Study
Mendelian Randomization Analysis
Nutritional Status
Polymorphism, Single Nucleotide

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PMID: 34601600
DOI: 10.1093/jn/nxab348
PMCID: PMC8754580

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