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The alphavirus determinants of intercellular long extension formation

19 Dec 2024

Abstract excerpt

The alphavirus chikungunya virus (CHIKV) is a serious human pathogen that can cause large-scale epidemics characterized by fever and joint pain and often resulting in chronic arthritis. Infection by alphaviruses including CHIKV and the closely related Semliki Forest virus (SFV) can induce the formation of filopodia-like intercellular long extensions (ILEs). ILEs emanate from an infected cell, stably attach to a...

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PMID: 39699169
DOI: 10.1128/mbio.01986-24

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