Article
Intercellular Extensions Are Induced by the Alphavirus Structural Proteins and Mediate Virus Transmission
15 Dec 2016
Abstract excerpt
Alphaviruses are highly organized enveloped RNA viruses with an internal nucleocapsid surrounded by a membrane containing the E2 and E1 transmembrane proteins. Alphavirus budding takes place at the plasma membrane and requires the interaction of the cytoplasmic domain of E2 with the capsid protein. Here we used WT alphaviruses and Sindbis virus in which E2 was fused to a fluorescent protein to characterize virus...
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