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Changes in DNA methylation are associated with systemic lupus erythematosus flare remission and clinical subtypes

18 Dec 2024

Abstract excerpt

BACKGROUND: Systemic lupus erythematosus (SLE) has numerous symptoms across organs and an unpredictable flare-remittance pattern. This has made it challenging to understand drivers of long-term SLE outcomes. Our objective was to identify whether changes in DNA methylation over time, in an actively flaring SLE cohort, were associated with remission and whether these changes meaningfully subtype SLE patients....

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PMID: 39696438
DOI: 10.1186/s13148-024-01792-x

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