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Article

Influence of UDP-glucuronosyltransferase polymorphisms on mycophenolate mofetil-induced side effects in kidney transplant patients.

Transplantation proceedings - 1 Apr 2008

Betônico G N, Abbud-Filho M, Goloni-Bertollo E M, Alvarenga M P S, Guillemette C, Villeneuve L, Benoit-Biancamano M-O, Pavarino-Bertelli E C

Abstract excerpt

Mycophenolate mofetil (MMF) is an immunosuppressive prodrug approved for use in transplantation. Its active metabolite, mycophenolic acid, is mainly metabolized by UDP-glucuronosyltransferase (UGT) enzymes. In this study, we retrospectively analyzed 74 kidney transplant patients who had been prescribed MMF as part of their immunosuppression regimen. Polymorphisms in UGT1A8 (-999C > T, codon 255A > G, codon 277G >...

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Identifiers

PMID: 18454993
DOI: 10.1016/j.transproceed.2008.03.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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