An evaluation of heterologous antibodies to lactate dehydrogenase-C in the detection of mutations.

doi:10.1016/0027-5107(85)90217-9

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Article

An evaluation of heterologous antibodies to lactate dehydrogenase-C in the detection of mutations.

Mutation research - 1 Jan 2000

Burkhart J G, Benziger J, Svensson K, Malling H V

Abstract excerpt

We report that we are unable to repeat consistently the results published by Ansari et al. (1980) using antibodies to detect mutations in lactate dehydrogenase-C (LDH-C, previously called LDH-X) directly in sperm of mice exposed to the mutagen procarbazine. The approach made use of the interspeci...

Topics

Animals
Antibody Specificity
Cross Reactions
Isoenzymes
L-Lactate Dehydrogenase
Male
Mice
Mutation
Spermatozoa
Temperature

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