Article
An evaluation of heterologous antibodies to lactate dehydrogenase-C in the detection of mutations.
Mutation research - 1 Jan 2000
Burkhart J G, Benziger J, Svensson K, Malling H V
Abstract excerpt
We report that we are unable to repeat consistently the results published by Ansari et al. (1980) using antibodies to detect mutations in lactate dehydrogenase-C (LDH-C, previously called LDH-X) directly in sperm of mice exposed to the mutagen procarbazine. The approach made use of the interspecies differences in the antigenic sites between the LDH-C of the rat and mouse in sperm. The visualization of mutations...
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