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Article

Epitope mapping via in vitro deep mutational scanning methods and its applications

13 Dec 2024

Abstract excerpt

Epitope mapping is a technique employed to define the region of an antigen that elicits an immune response, providing crucial insight into the structural architecture of the antigen as well as epitope-paratope interactions. With this breadth of knowledge, immunotherapies, diagnostics, and vaccines are being developed with a rational and data-supported design. Traditional epitope mapping methods are laborious,...

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PMID: 39674321
DOI: 10.1016/j.jbc.2024.108072

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