Article
Uterine fibroids show evidence of shared genetic architecture with blood pressure traits.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2025
Akerele Alexis T, Piekos Jacqueline A, Kim Jeewoo, Khankari Nikhil K, Hellwege Jacklyn N, Edwards Todd L, Velez Edwards Digna R
Abstract excerpt
Uterine leiomyomata (fibroids, UFs) are common, benign tumors in females, having an estimated prevalence of up to 80%. They are fibrous masses growing within the myometrium leading to chronic symptoms like dysmenorrhea, abnormal uterine bleeding, anemia, severe pelvic pain, and infertility. Hypertension (HTN) is a common risk factor for UFs, though less prevalent in premenopausal individuals. While observational...
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