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Article

Blood Pressure, Cardiometabolic Traits, and Cardiovascular Events in Women With Uterine Fibroids: A Genetic Correlation and Mendelian Randomization Study.

Journal of the American Heart Association - 15 Apr 2025

Henry Joséphine, Berrandou Takiy, Brewster Lizzy M, Bouatia-Naji Nabila

Abstract excerpt

BACKGROUND: Uterine fibroids (UFs) are understudied uterus neoplasms, mainly affecting women of reproductive age and often leading to hysterectomy. Clinical series suggest impaired cardiometabolic features in UFs. We investigated potential genetic links between blood pressure (BP), several cardiometabolic traits, and UFs. METHODS AND RESULTS: We used summary statistics of genome-wide association studies for UFs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40207525
DOI: 10.1161/JAHA.124.036697
PMCID: PMC12132859

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