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Over 1000 genetic loci influencing blood pressure with multiple systems and tissues implicated

13 Aug 2019

Abstract excerpt

High blood pressure (BP) remains the major heritable and modifiable risk factor for cardiovascular disease. Persistent high BP, or hypertension, is a complex trait with both genetic and environmental interactions. Despite swift advances in genomics, translating new discoveries to further our understanding of the underlying molecular mechanisms remains a challenge. More than 500 loci implicated in the regulation...

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PMID: 31411675
DOI: 10.1093/hmg/ddz197

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