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Article

Differential Impact of Spike Protein Mutations on SARS-CoV-2 Infectivity and Immune Evasion: Insights from Delta and Kappa Variants.

Journal of microbiology and biotechnology - 28 Dec 2024

Kim Tae-Hun, Bae Sojung, Myoung Jinjong

Abstract excerpt

SARS-CoV-2 continues to pose a global health challenge due to its high transmissibility and mutability, with new variants emerging that potentially undermine vaccination and therapeutic efforts. Mutations in the spike protein, particularly in the receptor-binding domain (RBD), significantly influence viral transmissibility and immune escape. However, the complex interplay of these mutations and their combined...

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Identifiers

PMID: 39631784
DOI: 10.4014/jmb.2411.11001

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