Article
Reduced sensitivity of the SARS-CoV-2 Lambda variant to monoclonal antibodies and neutralizing antibodies induced by infection and vaccination.
Emerging microbes & infections - 1 Dec 2022
Wang Meiyu, Zhang Li, Li Qianqian, Wang Bo, Liang Ziteng, Sun Yeqing, Nie Jianhui, Wu Jiajing, Su Xiaodong, Qu Xiaowang, Li Yuhua, Wang Youchun, Huang Weijin
Abstract excerpt
Severe acute respiratory syndrome coronavirus 2 variants have continued to emerge in diverse geographic locations with a temporal distribution. The Lambda variant containing multiple mutations in the spike protein, has thus far appeared mainly in South America. The variant harbours two mutations in the receptor binding domain, L452Q and F490S, which may change its infectivity and antigenicity to neutralizing...
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