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Mutations of SARS-CoV-2 spike protein: Implications on immune evasion and vaccine-induced immunity.

Seminars in immunology - 1 Jun 2021

Mengist Hylemariam Mihiretie, Kombe Kombe Arnaud John, Mekonnen Daniel, Abebaw Abtie, Getachew Melese, Jin Tengchuan

Abstract excerpt

Responsible for more than 4.9 million deaths so far, COVID-19, caused by SARS-CoV-2, is instigating devastating effects on the global health care system whose impacts could be longer for the years to come. Acquiring a comprehensive knowledge of host-virus interaction is critical for designing effective vaccines and/or drugs. Understanding the evolution of the virus and the impact of genetic variability on host...

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COVID-19
COVID-19 Vaccines
Immune Evasion
Mutation
SARS-CoV-2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Spike Glycoprotein, Coronavirus

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Identifiers

PMID: 34836774
DOI: 10.1016/j.smim.2021.101533
PMCID: PMC8604694

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