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Mitochondrial and Nuclear Mitochondrial Variants in Allergic Diseases

1 Jan 2020

Abstract excerpt

The mitochondrial genome encodes core catalytic peptides that affect major metabolic processes within a cell. Here, we investigated the association between mitochondrial DNA (mtDNA) variants and allergic diseases, including atopic dermatitis (AD) and asthma, alongside heteroplasmy within the mtDNA in subjects with allergic sensitization. We collected genotype data from 973 subjects with allergic sensitization,...

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PMID: 32638566
DOI: 10.4168/aair.2020.12.5.877

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