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Genetic insights into kidney stone formation: a Mendelian randomization study of protein quantitative trait loci.

Urolithiasis - 30 Nov 2024

Huang Haoxiang, Chen Bohong, Feng Cong, Chen Wei, Wu Dapeng

Abstract excerpt

Kidney stones are a common urological condition caused by a complex interaction of genetic, metabolic, and environmental factors. Recent genomic research has shed light on the genetic basis of kidney stone susceptibility.This study aims to identify protein quantitative trait loci (pQTL) associated with kidney stone formation and explore their causal relationships using Mendelian randomization.We conducted...

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Genetic Predisposition to Disease
Genome-Wide Association Study
Kidney Calculi
Mendelian Randomization Analysis
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Interaction Maps

Quantitative Trait Loci

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PMID: 39614878
DOI: 10.1007/s00240-024-01667-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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