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Article

Genetically predicted 91 circulating inflammatory proteins in relation to risk of urological malignancies: a Mendelian randomization study.

Aging - 13 Jun 2024

Xu Jianxiong, Chen Ru, Yang Yucheng, Xu Sufang, Yao Lijing

Abstract excerpt

BACKGROUND: Urological malignancies, including kidney, bladder, and prostate cancer, are major health concerns worldwide. Inflammation has been implicated in the pathogenesis of these cancers, and circulating inflammatory proteins may play a role in their development. However, the causal relationship between specific plasma proteins and urological malignancies remains unclear. METHODS: We performed a two-sample...

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Blood Proteins
Genome-Wide Association Study
Inflammation
Kidney Neoplasms
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prostatic Neoplasms

Urinary Bladder Neoplasms

Urologic Neoplasms

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PMID: 38874503
DOI: 10.18632/aging.205934
PMCID: PMC11236305

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