Article
Causal effects of modifiable risk factors on kidney stones: a bidirectional mendelian randomization study.
BMC medical genomics - 20 Apr 2023
Liu Wen, Wang Miaomiao, Liu Jianyong, Yan Qiuxia, Liu Ming
Abstract excerpt
BACKGROUND: Increasing epidemiological studies demonstrated that modifiable risk factors affected the risk of kidney stones. We aimed to systemically assess these causal associations using a bidirectional Mendelian randomization study. METHODS: We obtained instrumental variables related to each exposure at the genome-wide significant threshold (P < 5 × 10-8). Summary level data for outcomes from the FinnGen...
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