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Article

The TRIM37 variant rs57141087 contributes to triple-negative breast cancer outcomes in Black women.

EMBO reports - 1 Jan 2025

Tihagam Rachisan Djiake, Lou Song, Zhao Yuanji, Liu Kammi Song-Yan, Singh Arjun Tushir, Koo Bon Il, Przanowski Piotr, Li Jie, Huang Xiaosong, Li Hong, Tushir-Singh Jogender, Fejerman Laura, Bhatnagar Sanchita

Abstract excerpt

Triple-negative breast cancer (TNBC) disproportionately affects younger Black women, who show more aggressive phenotypes and poorer outcomes than women of other racial identities. While the impact of socioenvironmental inequities within and beyond health systems is well documented, the genetic influence in TNBC-associated racial disparities remains elusive. Here, we report that cancer-free breast tissue from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Promoter Regions, Genetic

Share to Tripartite Motif Proteins

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Source

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Identifiers

PMID: 39614126
DOI: 10.1038/s44319-024-00331-2
PMCID: PMC11723928

Genes

TRIM37
NRF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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