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Article

HSD17B7 gene in self‐renewal and oncogenicity of keratinocytes from Black versus White populations

29 Jun 2021

Abstract excerpt

Human populations of Black African ancestry have a relatively high risk of aggressive cancer types, including keratinocyte-derived squamous cell carcinomas (SCCs). We show that primary keratinocytes (HKCs) from Black African (Black) versus White Caucasian (White) individuals have on average higher oncogenic and self-renewal potential, which are inversely related to mitochondrial electron transfer chain activity...

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PMID: 34185380
DOI: 10.15252/emmm.202114133

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