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Article

BRAF V600E-Mutant Acute Myeloid Leukemia: A Case Series and Literature Review of a Rare Entity.

Genes - 28 Oct 2024

George Giby V, Evans Andrew G, Jajosky Audrey N

Abstract excerpt

Background: Although BRAF V600E mutations are common in solid tumors and select hematologic neoplasms, they are reported less frequently in myeloid malignancies. Of the cases of BRAF V600E-mutant acute myeloid leukemia (AML) that have been described, most display monocytic morphology and concurrent KMT2A rearrangement. Strikingly, all cases have been associated with poor survival. Case Presentation: Here, we...

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Share to Histone-Lysine N-Methyltransferase
Share to Leukemia, Myeloid, Acute

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Myeloid-Lymphoid Leukemia Protein

Share to Proto-Oncogene Proteins B-raf

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Identifiers

PMID: 39596583
DOI: 10.3390/genes15111383
PMCID: PMC11593820

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