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KMT2A (MLL) fusions in aggressive sarcomas in young adults

28 May 2019

Abstract excerpt

AIM: To characterise unclassifiable sarcomas by use of a combined histological and molecular approach. METHODS AND RESULTS: Using RNA sequencing, we identified in-frame fusions involving KMT2A (MLL) in two cases. Case 1 was a 20-year-old woman with a deep soft tissue mass in the thigh. The tumour consisted of monomorphic round, epithelioid and spindle cells in a highly sclerotic background that were focally...

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PMID: 31136005
DOI: 10.1111/his.13926

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