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BRAF mutation in myeloid neoplasm: incidences and clinical outcomes.

Leukemia & lymphoma - 1 Sept 2024

Abuasab Tareq, Mohamed Shehab, Pemmaraju Naveen, Kadia Tapan M, Daver Naval, DiNardo Courtney D, Ravandi Farhad, Qiao Wei, Montalban-Bravo Guillermo, Borthakur Gautam

Abstract excerpt

The presence of BRAF mutation in hematological malignancies, excluding Hairy cell leukemia, and its significance as a driver mutation in myeloid neoplasms (MNs) remains largely understudied. This research aims to evaluate patient characteristics and outcomes of BRAF-mutated MNs. Among a cohort of 6667 patients, 48 (0.7%) had BRAF-mutated MNs. Notably, three patients exhibited sole BRAF mutation, providing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38696743
DOI: 10.1080/10428194.2024.2347539

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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