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Article

Impact of Rab27 on Melanoma Cell Invasion and sEV Secretion

19 Nov 2024

Abstract excerpt

The migratory and invasive capabilities of melanoma cells contribute to metastasis. Therefore, targeting the genes driving these processes can support melanoma therapy. Rab27A and Rab27B contribute to tumor formation progression in many types of cancer through various mechanisms, including the secretion of small extracellular vesicles (sEVs). We explored the role of these GTPases in melanoma cell functioning in...

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PMID: 39596498
DOI: 10.3390/ijms252212433

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