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Revealing the role of RAB27 in HER receptor family expression and signaling in melanoma cells

4 Mar 2025

Abstract excerpt

BACKGROUND: Alterations in signalling pathways fuel the growth and progression of melanoma. Therefore, understanding these processes is essential for developing effective treatment strategies. RAB27A and RAB27B are known to possess oncogenic effects by modulating cancer cell proliferation, invasion and drug resistance in various types of cancer, including melanoma. These proteins are mostly acknowledged as...

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PMID: 40038749
DOI: 10.1186/s12964-025-02064-8

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