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Article

Tissue-Specific Effects of Aging on Repeat-Mediated Mutation Hotspots In Vivo.

Biomolecules - 16 Nov 2024

D'Amico Alexandra M, Li Tonia T, Vasquez Karen M

Abstract excerpt

Aging constitutes complex and dynamic alterations in molecular and physiological processes and is associated with numerous disorders, in part due to increased genetic instability. The aging population is projected to double by 2050, underscoring the urgent need to better understand the relationships between aging and age-related disorders. Repetitive DNA elements are intrinsic sources of genetic instability and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39595629
DOI: 10.3390/biom14111453
PMCID: PMC11592361

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MYC

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