Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CRIPTO’s multifaceted role in driving aggressive prostate cancer unveiled by in vivo, organoid, and patient data

26 Nov 2024

Abstract excerpt

Abstract CRIPTO (or CR-1 or TDGF1) is a protein that plays an active role in tumor initiation and progression. We have confirmed that increased expression of CRIPTO is associated with clinical and prostate-specific antigen (PSA) progression in human prostate tissues. Our approach involved gaining insight into the role of CRIPTO signaling in castration-resistant Nkx3.1-expressing cells (CARNs), targets for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Hippo pathway signaling and YAP/TAZ
Share to Prostate Cancer Treatment and Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39592836
DOI: 10.1038/s41388-024-03230-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CRIPTO’s multifaceted role in driving aggressive prostate cancer unveiled by in vivo, organoid, and patient dataPMID 39592836Read ↗

Single cell analysis of cribriform prostate cancer reveals cell intrinsic and tumor microenvironmental pathways of aggressive diseaseSemantic proximity Read ↗

Epigenetic Derepression of PROX1 Promotes Neuroendocrine Prostate Cancer ProgressionSemantic proximity Read ↗

Conditionally Reprogrammed Cells from Patient-Derived Xenograft to Model Neuroendocrine Prostate Cancer DevelopmentSemantic proximity Read ↗

The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1Semantic proximity Read ↗

Single-cell transcriptional regulation and genetic evolution of neuroendocrine prostate cancerSemantic proximity Read ↗

Epigenetic remodeling and 3D chromatin reorganization governed by NKX2-1 drive neuroendocrine prostate cancerSemantic proximity Read ↗

Unraveling the Complexity of Prostate Adenocarcinoma: Integrative Insights from Spatial Transcriptome and Single Cell AnalysisSemantic proximity Read ↗

Multilineage plasticity in prostate cancer through expansion of stem–like luminal epithelial cells with elevated inflammatory signalingSemantic proximity Read ↗

The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1Semantic proximity Read ↗

Targeting the TLK1-Nek1-Mediated Activation of YAP1 Attenuates PD-L1 and Anti-Inflammation Set for Prostate Cancer ImmunoevasionSemantic proximity Read ↗

Longitudinal single-cell profiling links RUNX1T1 to lineage transition and maintenance in treatment-induced neuroendocrine prostate cancerSemantic proximity Read ↗

Generation of prostate cancer assembloids modeling the patient-specific tumor microenvironmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.