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Morphoregulatory ADD3 underlies glioblastoma growth and formation of tumor–tumor connections

26 Nov 2024

Abstract excerpt

Glioblastoma is a major unmet clinical need characterized by striking inter- and intra-tumoral heterogeneity and a population of glioblastoma stem cells (GSCs), conferring aggressiveness and therapy resistance. GSCs communicate through a network of tumor-tumor connections (TTCs), including nanotubes and microtubes, promoting tumor progression. However, very little is known about the mechanisms underlying TTC...

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PMID: 39592188
DOI: 10.26508/lsa.202402823

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