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Article

Impact of endogenous viral elements on glioma clinical phenotypes by inducing OCT4 in the host.

Frontiers in cellular and infection microbiology - 1 Jan 2024

Li Shirong, He Shuai, Xue Haoyu, He Yi

Abstract excerpt

Introduction: Endogenous viral elements (EVEs) are viral sequences integrated within the host genome that can influence gene regulation and tumor development. While EVEs have been implicated in cancer, their role in regulating key transcription factors in glioblastoma (GBM) remains underexplored. This study investigates the relationship between EVEs and the activation of OCT4, a critical transcription factor in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39588508
DOI: 10.3389/fcimb.2024.1474492
PMCID: PMC11586349

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