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The shared genetic landscape of polycystic ovary syndrome and breast cancer: convergence on ER + breast cancer but not ER- breast cancer.

Breast cancer research : BCR - 25 Nov 2024

Bi Kaixin, Chen Miaoran, Zhao Qianru, Yang Tongtong, Xie Wenjia, Ma Wenqi, Jia Hongyan

Abstract excerpt

BACKGROUND: The clinically high comorbidity between polycystic ovary syndrome (PCOS) and breast cancer (BC) has been extensively reported. However, limited knowledge exists regarding their shared genetic basis and underlying mechanisms. METHOD: Leveraging summary statistics from the largest genome-wide association studies (GWASs) to date, we conducted a comprehensive genome-wide cross-trait analysis of PCOS and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 39587695
DOI: 10.1186/s13058-024-01923-5
PMCID: PMC11587662

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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