Article
A Practical Approach to High-Throughput and Accurate Mapping-by-Sequencing in Arabidopsis.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2025
Tomaštíková Eva Dvořák, Pecinka Ales
Abstract excerpt
Forward-directed genetic screens are extremely powerful in identifying novel genes involved in a specific biological process, including various chromatin regulatory pathways. However, the traditional ways of genetic mapping are time- and cost-demanding. Recently, the whole process was revolutionized by the development of mapping-by-sequencing (MBS) protocols. In MBS, the causal mutations and their positions...
Topics
- Arabidopsis
- Chromosome Mapping
- High-Throughput Nucleotide Sequencing
- Genome, Plant
- Computational Biology
- Mutation
- Phenotype
- Whole Genome Sequencing