Article
Effective Mapping by Sequencing to Isolate Causal Mutations in the Tomato Genome.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Yuste-Lisbona Fernando J, Jiménez-Gómez José M, Capel Carmen, Lozano Rafael
Abstract excerpt
Forward genetic analysis remains as one of the most powerful tools for assessing gene functions, although the identification of the causal mutation responsible for a given phenotype has been a tedious and time-consuming task until recently. Advances in deep sequencing technologies have provided new approaches for the exploitation of natural and artificially induced genetic diversity, thus accelerating the...
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