Article
Identification of causal metabolites related to multiple autoimmune diseases.
Human molecular genetics - 21 Feb 2022
Yu Xing-Hao, Cao Rong-Rong, Yang Yi-Qun, Lei Shu-Feng
Abstract excerpt
Observational studies provide evidence that metabolites may be involved in the development of autoimmune diseases (ADs), but whether it is causal is still unknown. Based on the large-scale genome-wide association studies (GWAS) summary statistics, we performed two-sample Mendelian randomization (MR) to evaluate the causal associations between human blood metabolites and multiple ADs, which were inflammatory bowel...
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