Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population.

doi:10.1002/art.23494

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Article

Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population.

Arthritis and rheumatism - 1 Jul 2008

Kobayashi Shu, Ikari Katsunori, Kaneko Hirotaka, Kochi Yuta, Yamamoto Kazuhiko, Shimane Kenichi, Nakamura Yusuke, Toyama Yoshiaki, Mochizuki Takeshi, Tsukahara So, Kawaguchi Yasushi, Terai Chihiro, Hara Masako, Tomatsu Taisuke, Yamanaka Hisashi, Horiuchi Takahiko, Tao Kayoko, Yasutomo Koji, Hamada Daisuke, Yasui Natsuo, Inoue Hiroshi, Itakura Mitsuo, Okamoto Hiroshi, Kamatani Naoyuki, Momohara Shigeki

Abstract excerpt

OBJECTIVE: STAT4 encodes a transcriptional factor that transmits signals induced by several key cytokines, and it might be a key molecule in the development of autoimmune diseases. Recently, a STAT4 haplotype was reported to be associated with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) in Caucasian populations. This was replicated in a Korean RA population. Interestingly, the degree of risk...

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Identifiers

PMID: 18576330
DOI: 10.1002/art.23494

Genes

STAT4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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