Parental Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Predominates Over Coinfected SARS-CoV-2 Delta, Producing Less Lethal Variants in a Long-Term Replication Mouse Model.

Abstract excerpt

The evolution of SARS-CoV-2, which limits public control and treatment, seems to have occurred through multiple mechanisms, including recombination of cocirculating strains in hosts. However, insufficient experimental data have been obtained after coinfection. Therefore, we investigated the emergence of variants after coinfection with parental SARS-CoV-2 and the SARS-CoV-2 Delta. We found that fewer...

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