High-grade B-cell lymphoma not otherwise specified, with diffuse large B-cell lymphoma gene expression signatures: Genomic analysis and potential therapeutics.

doi:10.1002/ajh.27513

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Article

High-grade B-cell lymphoma not otherwise specified, with diffuse large B-cell lymphoma gene expression signatures: Genomic analysis and potential therapeutics.

American journal of hematology - 1 Jan 2025

Lone Waseem, Bouska Alyssa, Herek Tyler A, Amador Catalina, Song Joo, Xu Alexander M, Jochum Dylan, Issa Issa Ismail, Weisenburger Dennis D, Zhang Xuan, Bhagavathi Sharath Kumar, Heavican-Foral Tayla B, Sharma Sunandini, Shah Ab Rauf, Mir Abdul Rouf, Alkhinji Aisha Ahmad, El-Gamal Dalia, Dave Bhavana J, Hartert Keenan, Yu Jiayu, Saumyaranjan Mallick, Greiner Timothy C, Vose Julie, McKeithan Timothy W, Fu Kai, Green Michael, Bi Chengfeng, Merchant Akil, Chan Wing C, Iqbal Javeed

Abstract excerpt

High-grade B-cell lymphoma not otherwise specified (HGBCL, NOS) has overlapping morphological and genetic features with diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL), leading to uncertainty in its diagnosis and clinical management. Using functional genomic approaches, we previously characterized HGBCL and NOS, that demonstrate gene expression profiling (GEP), and genetic signatures similar to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39548807
DOI: 10.1002/ajh.27513
PMCID: PMC11625982

Genes

PIM1
CCND3
PRDM1
TP53
ASPM
BCL6
CARD11
CD79B
CDKN2A
DDX3X
GNA13
KMT2D
MYD88
RB1
REL
STAT3
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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