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A multi-epitope subunit vaccine providing broad cross-protection against diverse serotypes of Streptococcus suis

14 Nov 2024

Abstract excerpt

Streptococcus suis infection represents a major challenge in pig farming and public health due to its zoonotic potential and diverse serotypes, while existing vaccines lack effective cross-protection. This study employed reverse vaccinology and immunoinformatics to identify 8 conserved proteins across 11 prevalent serotypes of S. suis. 16 candidate epitopes were selected to design three multi-epitope antigens...

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PMID: 39543108
DOI: 10.1038/s41541-024-01015-7

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