Design of Staphylococcus aureus New Vaccine Candidates with B and T Cell Epitope Mapping, Reverse Vaccinology, and Immunoinformatics

Abstract excerpt

An effective vaccine against Staphylococcus aureus infection is a major planetary heath priority, particularly with increasing antibiotic resistance worldwide. Previous efforts for a highly effective S. aureus vaccine were largely unsuccessful, in part, because the vaccine designs have tended to target mainly the B cell immunity and development of opsonic antibodies. In contrast, recent observations suggest that...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biochemical and Structural Characterization
• Share to Peptidase Inhibition and Analysis
• Share to vaccines and immunoinformatics approaches