Article
Identification of cross-reactive vaccine antigen candidates in Gram-positive ESKAPE pathogens through subtractive proteome analysis using opsonic sera
2025-02-08
Abstract excerpt
The Gram-positive pathogens of the ESKAPE group, Enterococcus faecium, and Staphylococcus aureus , are well-known to pose a serious risk to human health because of their high virulence and numerous drug resistances, making them a real concern in healthcare settings worldwide. To narrow down the list of previously identified promising protein vaccine candidates, a combination of several antigen discovery approach...
Topics
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- Antimicrobial Resistance in Staphylococcus
- Bacterial Infections and Vaccines
- Biochemical and Structural Characterization
- Escherichia coli research studies
- Monoclonal and Polyclonal Antibodies Research
- Pneumonia and Respiratory Infections
- Streptococcal Infections and Treatments
- vaccines and immunoinformatics approaches
Identifiers and source
- Literature Corpus work
- a7866e69-b20e-51a5-8588-dfd1153919c0
- DOI
- 10.1101/2025.02.06.636871
