Article
Immunogenic Responses Elicited by a Pool of Recombinant <em>Lactiplantibacillus plantarum</em> NC8 Strains Surface-Displaying Diverse African Swine Fever Antigens Administered via Different Immunization Routes in a Mouse Model
2025-05-21
Abstract excerpt
<h4>Background: </h4> African swine fever (ASF) is a deadly, highly contagious disease with major global pig industry impacts, highlighting the urgent need for an effective vaccine. <h4>Methods:</h4> In this study, six antigenic proteins (K78R, A104R, E120R, E183L, D117L, and H171R) of ASFV were fused with the LPxTG surface anchoring polypeptide i.e., LP3065 of Lactobacillus plantarum WCFS1, resulting in the gener...
Topics
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- Animal Disease Management and Epidemiology
- Monoclonal and Polyclonal Antibodies Research
- Streptococcal Infections and Treatments
- Toxin Mechanisms and Immunotoxins
- vaccines and immunoinformatics approaches
- Vector-Borne Animal Diseases
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
Identifiers and source
- Literature Corpus work
- 682f9fba-6eca-5d45-bc25-ec8c7a78407c
- DOI
- 10.20944/preprints202505.1701.v1
