Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

OpcA and PorB are novel bactericidal antigens of the 4CMenB vaccine in mice and humans

12 Apr 2023

Abstract excerpt

The ability of Neisseria meningitidis Outer Membrane Vesicles (OMV) to induce protective responses in humans is well established and mainly attributed to Porin A (PorA). However, the contribution of additional protein antigens to protection remains to be elucidated. In this study we dissected the immunogenicity of antigens originating from the OMV component of the 4CMenB vaccine in mice and humans. We collected...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amoebic Infections and Treatments
Share to Bacterial Infections and Vaccines
Share to Pneumonia and Respiratory Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37045859
DOI: 10.1038/s41541-023-00651-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

OpcA and PorB are novel bactericidal antigens of the 4CMenB vaccine in mice and humansPMID 37045859Read ↗

The Development of a Vaccine Against Meningococcus B Using Reverse VaccinologySemantic proximity Read ↗

Immunoproteomic Analysis of the Development of Natural Immunity in Subjects Colonized by Neisseria meningitidis Reveals Potential Vaccine CandidatesSemantic proximity Read ↗

A novel meningococcal outer membrane vesicle vaccine with constitutive expression of FetA: A phase I clinical trialSemantic proximity Read ↗

Identification of Vaccine Candidates Against Serogroup B Meningococcus by Whole-Genome SequencingSemantic proximity Read ↗

Correlates of protection for meningococcal surface protein vaccines: current approaches for the determination of breadth of coverageSemantic proximity Read ↗

Immunological fingerprint of 4CMenB recombinant antigens via protein microarray reveals key immunosignatures correlating with bactericidal activitySemantic proximity Read ↗

Looking beyond meningococcal B with the 4CMenB vaccine: the Neisseria effectSemantic proximity Read ↗

MATS: Global coverage estimates for 4CMenB, a novel multicomponent meningococcal B vaccineSemantic proximity Read ↗

Towards the Immunoproteome of Neisseria meningitidisSemantic proximity Read ↗

The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeaeSemantic proximity Read ↗

Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines.Semantic proximity Read ↗

Correlates of protection for meningococcal surface protein vaccines: lessons from the pastSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.