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Germline Genetic Susceptibility Testing Among Emirati Nationals at Risk for Hereditary Breast and Ovarian Cancer Syndrome.

JCO global oncology - 1 Nov 2024

Rawashdeh Rifaat R, Pederson Holly, Iskanderian Rafal, Khan Fawad, Altrabulsi Basel, Ricci Stephanie, Eng Charis, Jallad Bassel, Al Mannaei Asma Ibrahim, Alameri Mohamed Salem, Attia Azza, Grobmyer Stephen R

Abstract excerpt

PURPOSE: Breast cancer among Emirati patients is characterized by early-onset disease and later stages at presentation. Little is known about the germline genetic variants that may contribute to these observations. The goal of this study is to characterize the rate and implications of germline genetic variants among a cohort of Emirati patients at risk for hereditary breast and ovarian cancer syndrome. MATERIALS...

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PMID: 39541563
DOI: 10.1200/GO-24-00352

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