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Article

The spectrum of BRCA1 and BRCA2 alleles in Latin America and the Caribbean: a clinical perspective.

Breast cancer research and treatment - 1 Dec 2015

Dutil Julie, Golubeva Volha A, Pacheco-Torres Alba L, Diaz-Zabala Hector J, Matta Jaime L, Monteiro Alvaro N

Abstract excerpt

Hereditary cancer predisposition gene testing allows the identification of individuals at high risk of cancer that may benefit from increased surveillance, chemoprevention, and prophylactic surgery. In order to implement clinical genetic strategies adapted to each population's needs and intrinsic genetic characteristic, this review aims to present the current status of knowledge about the spectrum of BRCA...

Topics

BRCA1 Protein
BRCA2 Protein
Breast Neoplasms
Caribbean Region
Female
Gene Frequency
Genetic Predisposition to Disease
Genetic Testing
Genetics, Population
Hispanic or Latino

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Latin America

Mutation

Ovarian Neoplasms

United States

Source

Open in PubMed Open full text

Identifiers

PMID: 26564481
DOI: 10.1007/s10549-015-3629-3
PMCID: PMC4661195

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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