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Article

Identification and functional analysis of six melanocortin-4-receptor-like (MC4R-like) mutations in goldfish (Carassius auratus).

General and comparative endocrinology - 1 Jan 2025

Wang Ying, Yang Tianze, Mo Haolin, Yao Mingxing, Song Qingchuan, Yu Huixia, Du Yuyou, Li Yang, Yu Jiajia, Wang Lixin

Abstract excerpt

Melanocortin receptor-4 (MC4R) belongs to the G protein-coupled receptor family, characterized by a classical structure of seven transmembrane domains (7TMD). They play an important role in food intake and weight regulation. In the present study, we identified melanocortin-4-receptor-like (caMC4RL) mutants of goldfish from the Qian River in the Qin Ling region and characterized their functional properties,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39536983
DOI: 10.1016/j.ygcen.2024.114639

Genes

MC4R

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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