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Article

The melanocortin-4 receptor: physiology, pharmacology, and pathophysiology.

Endocrine reviews - 1 Aug 2010

Tao Ya-Xiong

Abstract excerpt

The melanocortin-4 receptor (MC4R) was cloned in 1993 by degenerate PCR; however, its function was unknown. Subsequent studies suggest that the MC4R might be involved in regulating energy homeostasis. This hypothesis was confirmed in 1997 by a series of seminal studies in mice. In 1998, human gen...

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Identifiers

PMID: 20190196
DOI: 10.1210/er.2009-0037
PMCID: PMC3365848

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20190196-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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