A conserved interaction between the effector Sca4 and host clathrin suggests additional contributions for Sca4 during rickettsial infection

Abstract excerpt

ABSTRACT Intracellular bacterial pathogens deploy secreted effector proteins that manipulate diverse host machinery and pathways to promote infection. Although many effectors carry out a single function or interaction, there are a growing number of secreted effectors capable of interacting with multiple host factors. However, few effectors secreted by arthropod-borne obligate intracellular Rickettsia species have...

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