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Toxoplasma gondii scavenges mammalian host organelles through the usurpation of host ESCRT-III and Vps4A

31 Jan 2023

Abstract excerpt

Intracellular pathogens exploit cellular resources through host cell manipulation. Within its nonfusogenic parasitophorous vacuole (PV), Toxoplasma gondii targets host nutrient-filled organelles and sequesters them into the PV through deep invaginations of the PV membrane (PVM) that ultimately detach from this membrane. Some of these invaginations are generated by an intravacuolar network (IVN) of...

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PMID: 36718630
DOI: 10.1242/jcs.260159

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